The Mengnuo syncline was formed in the late Yanshanian intracontinental orogenic stage. Based on the comparison among strata, lithology, tectonic characteristics, this paper focuses on the geological characters and metallogenetic regularity of the Eastern Mengnuo Pb-Zn deposit, and combines it with the analysis of the soil element geochemical anomaly in the Western Mnegnuo area. It is believed that there are great resources potentialities in the Western Mengnuo area and the depth of the syncline.